Sugammadex reversal and awakening

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Sugammadex: new questions on reversal.

Recently released in Brazil, sugammadex is a modified γ-cyclodextrin, which is showing favorable results regarding reversal of motor blockade, particularly by rocuronium. One of the main advantages of this agent over neostigmine is the reversal of relaxation when the patient is deeply curarized. However, the use of sugammadex in such conditions of deep blockade has shown a phenomenon not previo...

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ISSN © 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. Dear Editor, Sugammadex is a modifi ed gamma cyclodextrin . Cyclodextrins are water soluble cyclic oligosaccharides with a lipophilic core. Sugammadex has quickly found a place in clinical use for selective antagonism of neuromuscular blockade with rocuronium . Sugammadex quickly encapsulates steroidal neuro...

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Background: Sugammadex is a new reversal agent for nondepolarizing neuromuscular blockade. We conducted the randomized clinical study to compare the recovery between sugammadex alone and combined use of sugammadex and neostigmine. Methods: Forty adult patients were randomly allocated to Group S (n=20) or Group SN (n=20). General anesthesia was induced and maintained with propofol and remifentan...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 2020

ISSN: 0003-2409,1365-2044

DOI: 10.1111/anae.15002